Sunday, October 13, 2019

My personal Goals Essay -- essays research papers

  Ã‚  Ã‚  Ã‚  Ã‚   The personal goals that I want to achieve as a student of the University of Phoenix are in the education and career areas of my life. In my education, my major goal is to gain knowledge in computers and network administration, eventually culminating in a Bachelor of Science in Information Technology. I also wish to strengthen my grammar and interpersonal skills. In my career, my goal is to either advance from my current career as a paralegal to that of an office manager or to enter into a different career as information technology department administrator. I will use staff and university services in order to achieve my goals in a reasonable timeframe with limited obstacles. To achieve these goals I plan on using the University of Phoenix’s classes and academic services and to eventually use the degree I will receive from the university. To achieve my education goals I plan on using classes and academic services provided by the University of Phoenix. To strengthen my grammar and interpersonal skills, I plan on taking classes at the University of Phoenix that will give me more confidence and experience in writing and communication. I also plan on attending writing workshops that the University of Phoenix offers and use of the Center for Writing Excellence to help me as well. To gain knowledge and training in computer and network administration I plan on taking the computer courses that the University of Phoenix offers. I plan on taking computer-...

Saturday, October 12, 2019

An Analysis of ?The Meanings of Seneca Falls, 1848-1998? :: essays research papers fc

While being born in the modern times, no woman knows what it was like to have a status less than a man’s. It is hard to envision what struggles many women had to go through in order to get the rights to be considered equal. In the essay The Meanings of Seneca Falls, 1848-1998, Gerda Lerner recalls the events surrounding the great women’s movement. Among the several women that stand out in the movement, Elizabeth Cady Stanton stands out because of her accomplishments. Upon being denied seating and voting rights at the World Antislavery Convention of 1840, she was outraged and humiliated, and wanted change. Because of Elizabeth Cady Stanton’s great perseverance, the Seneca Falls Convention of 1848 was a success as well as a great influence on the future of women’s rights. The convention had several attendees with notable assiduousness to the cause. The founders were Elizabeth Cady Stanton and Lucretia Mott, a highly acclaimed speaker and abolitionist. She was even founder of the Philadelphia Female Anti-Slavery Society and its long-term president! Martha Wright, Jane Hunt, and Mary Ann McClintock were all women who worked in anti-slavery fairs that also wanted women’s rights (203). Among other attendees, Frederick Douglass was also present! With the notable group assembled, a road to change was starting to form. The women had very limited rights compared to men of the time. Women had no voice when it came to the law, they were deprived rights of citizenship, and deprived of their property and wages. They were also discriminated when the matters had to do with payment for work and divorce and were declared civilly dead up on marriage (204)! Finally, women were kept out of professions, and were to be kept as a dependent of the man. Half the population had their rights withheld because of the role that they were born into. The Seneca Falls Convention sought out to have these rights changed so that women could have the freedom that they deserved. The outcome of the meeting had a great effect. The movement started at Seneca Falls requested the concepts by demanding legal, property, civil rights, and changes in gender-role definition and the woman’s rights to her own body (205). At the time, it was known that â€Å"all men are created equal†. When the definition is taken literally, the rights of women are demeaned. However, the women believed that as citizens and members of society, they had the rights to be treated equal as any other man.

Friday, October 11, 2019

Cause and Effects essay Essay

There is no doubt that education is essential to people’s lives. Having a good educational background is an important factor to get a good job and to work effectively. However, one of the saddest issues in today’s society is the college dropout rate in many college or university remains very high. Some people are successful because they have the motivation and determination to graduate college; others are less lucky because they start college and feel as if they lack the preparation, desire, discipline or ability to succeed academically or persevere until a degree has been earned. This leads to quite a situation–to find the support needed to continue or to dropout? Whether you’re realizing that college isn’t for you, family issues, laziness or even debt, understanding some of the common causes and effects of quitting college may aid in the decision. College is an investment. Students either pay for college themselves, possibly with family support or scholarships, or with financial aid. Many students drop out of college because they can’t or don’t want to take on any more student loan debt. The consequence of dropping out at this point is that you have already piled up sizable debt and loan payments (students who drop out of college are required to pay back a portion of their federal-aid funds such as the Pell Grant) that you have to begin paying back several months after you quit school, yet you don’t get the payoff of a degree. Many financial aid administrators feel that the government shouldn’t penalize poor students for dropping out of college, and nor should lower-income students have to â€Å"punch a clock† in order to receive their grant money. Satisfying all the academic requirements and paying all your bills is both necessary and sufficient for being eligible to graduate. In addition to any debt you must repay, your earning potential without a degree is much lower to degree holders. Thus many college dropouts struggle to cover short-term bills and expenses, and find it difficult even to consider saving up money for a home. A college dropout earns about seven percent less than someone with an associate’s degree and about thirty-two percent less than someone with a bachelor’s. College dropouts face more limited career options than graduated peers. A bachelor’s degree commonly  opens the door to entry-level positions in many industries and career fields. As a dropout, your access to many jobs that require a college degree is limited to compete for jobs against people who hold degrees, even when a degree is not required. Job opportunities aren’t the only things that push people to college, sometimes it comes from a progenitor. Some students attend college under pressure from parents or to make their parents proud, not always making themselves happy in the process. In these cases the decision to drop out is not always warmly received. In fact, some students are told that they can’t return home after dropping out, which can only build on more stress. The expectation is that they will get a job and enter the â€Å"real world.† However, to get a job with good pay is hard to find without a degree, and most people don’t realize that. Another reason for dropping out of college is if there was a death in the family or someone you were close to falls ill. A death can cause depression which will eventually make you lose focus of your studies and you’ll end up either failing out, or dropping out. Dropping out can negatively affect relationships with significant others, as well. Recent studies show that divorce rates were significantly lower for college graduates than those without degrees. Having a great academic background can take you a long way, and you can learn how to work adequately in the future. To ensure a successful future, one must strive and have the incentive to succeed. Unfortunately certain things happen and some students have to drop out. It could be a personal choice, or it could be a sacrifice they have to make. In instances where it would be a choice, the students feel as if they’re working towards a dead end and have the lack of motivation. Knowing the reasons and the consequences can help others understand the decision that was made.

Thursday, October 10, 2019

Management of Creativity Essay

Bolman and Deal in their renowned Four Framework Approach declared that leaders all over the world tend to exhibit behaviour that fits in with one (of the 4) leadership models (or frameworks) suggested by them. These four models they christened as Structural, Political, Symbolic and Human Resource. Bolman and Deal suggest that of these models might prove either a success or a failure depending on the specific situation in which it is being used, particularly in the context of West End Musical theatre of Cambridge Theatre. In the following section, we take a closer look at three of these models. 1) The Structural Framework: In a successful condition, a leader following this leadership model will be a â€Å"social architect† who relies deeply on close inspection and detailed planning. These leaders will concentrate on factors such as structure, stratagem, setting, execution, trailing and adjustment. If however, his/her condition is unsuitable for this sort of leadership he/she will be found to be a bit of a bully and a ‘tyrant for details’. 2) The Political Framework – In the appropriate setting the ‘Political’ leader is an activist who tirelessly campaigns to help his followers cooperate and unite. Such leaders clearly spell out their needs and the means by which they intend to gain them. They are quick to gauge the distribution of capacity of the workers under him/her and the interests his/her establishment is likely to milk out of them. Building relations with the stakeholders will always be their first priority. For this, they will be likely to use persuasion and later negotiation or even a certain amount of force or pressure, if required. Of course, if the setting is unsuitable for this particular variety of leadership such leaders will prove grave failures and be seen as pushy and unscrupulous. 3) The Human Resource Framework – In a successful leadership setting a Human Resource leader is a medium or a channel who serves as supporter or a promoter and whose main occupation is to help empowerment. A typical Human Resource leader’s primary characteristic is his/her tremendous belief in people. However, it is not just their faith that ultimately makes them successful; instead, it is their capacity to communicate that faith. Such a leader is easily accessible and believes in keeping themselves available and in full view. They communicate their conviction in their workers strongly enough to convince them of their own capacities! They believe in increasing each staff-members contribution to the decision making process and in keeping their employees thoroughly informed. They empower their workforce and make them work as a whole, as a full-functional team where everyone is capable of making significant contributions. If the setting is, however not right for this variety of leadership such a leader will be found to be deceitful and deceptive. He/she may also be thought to abdicate from his duties and leave essential decision in the hands of less-experienced people who are not in any position to make important choices. (King, 2006) As if every successful leader comes to understand with time and experience no one, leadership model is adequately effective in all situations. Therefore, leaders often use various combinations of the four different models. In addition, it is also made quite clear that neither of these models is universally accepted in all situations and thus the style of leadership to be followed is largely dependant on the specific situation in which it is being applied. Take for instance the specific situation we have in hand. Given the major organizational modification that EEST is likely to undergo after its purchase by Oust a Structural leader rather than a purely visionary one will be more suitable for it. This is because Structural Leadership lays great amount of emphasis on ‘building’. Under the circumstances, EEST is in much need of this sort of structuring. Given the new employees and the burden of the old tasks of up gradation, EEST needs new strategies, new methodologies, new approaches and a completely new plan. A Structural Leader is capable of providing this better than others provide. Under the circumstances, the Director of Order Fulfilment Applications in the Information Technology department must therefore keep in mind that his/her, department (and Organization) is in dire need of ‘details’ that will allow it a new definition. As the leader the Director has the specific duty of providing these specific ‘details’, as of now. With time as the sudden changes settle down and ‘normality’ is established again, the Director may want to turn his/her attention to the level of growth and use Human Resource methods to step up progress. (Lamb, 2004) Despite our choice of one particular style of leadership, even during times of crisis (such as an organizational overhaul), we must keep in mind that no one leadership model can be our sole key to success. Our managerial capacities are proved only by means of our ability to combine and amalgamate various styles in order to obtain the results we are keen on achieving. For this, it is important for us to understand and tabulate our specific requirements and desired outcome before everything else. It is also of some value to understand our own selves and find out what our personal style of leadership is. Often our own unique approach, though theoretically quite inappropriate in a given situation, can prove to be a real savoir. As it is assumed that Cambridge Theatre lacked a proper form of leadership, it can be stated that with the help of these models it could have been more successful during its early days. It can well be stated that Leadership of multidisciplinary or interdisciplinary team of professionals under the aspects of Management principals can be defined as the art of creating industrial relations of any kind. This is between people engaged in the industry, such as relation between employers and employees, relation between individuals entering into commercial contracts, relation between investors etc, in order to maintain true cooperation of all concerned along with motivating the entire deal into a positive favour. Efficiency of the Leadership of multidisciplinary or interdisciplinary team of professionals lies in not only making the employees to work, but to make them work willingly, sincerely and consciously, by employing new knowledge, new methods, new designs, new machines and novel techniques of production and by allaying mistrust and antagonism. The Leadership purpose takes account of a several activities, and the most important among them is making a decision what staffing requirements one have and whether to use autonomous contractors or take into service employees to meet these needs. This is in accordance to appointing and training the excellent employees, making sure that they are better performers, handling performance related problems, and ensuring that the human resources and administrational practices do the accepted thing to various set of laws. Wright indicated in his book, The Moral Animal: why we are the way we are, that a fundamental supposition of Leadership of multidisciplinary or interdisciplinary team of professional’s approaches. It is that the whole staffs of the organization including both the management and the workers equally contributes to the common purpose, share the common objective and have full attention in progress of the organization. The Leadership policies and ideals undergo constant changes due to influence of some basic factors such as domestic and international competition, changes in the social structure and developments in technology etc. (Wright, 2000)

Wednesday, October 9, 2019

Analysis of gene research papers

Analysis of gene research papers Source: Ledford, H. (2017, March 07). CRISPR: gene editing is just the beginning. Retrieved July 05, 2017, from http://www.nature.com/news/crispr-gene-editing-is-just-the-beginning-1.19510 CRISPR has signaled a new age for molecular biologists, and non-profits like Addgene are on top of it all. Addgene has become the place where scientists deposit their tools while also turning to them in search of molecular tools. CRISPR now resembles something novel for researchers all around the world: Specificity – the ability to do exactly what they want and just what they want. The CRISPR tool can be used in many ways to suit the needs of the researcher. A common technique being used it to observe the effect of a change in the genetic code (particular genes) on the cell. This allows for a deeper understanding of metabolic pathways and effects of proteins and genes. The CRISPR associated protein 9 (CRISPR Cas9) is the enzyme which is in widespread use in laboratories. Researchers from Stanford University modified the Cas9 to just inhibit the gene, and not cutting the gene (as it would normally). The brilliancy of CRISPR is the fact that it itself has been modified and we can attach molecules that affect the epigenetics of the cell, that can be induced by specific stimuli and we can attach molecules that can even stimulate the expression of a particular gene. The ability of this tool to modify the epigenome with high specificity has massive implications as the epigenome has been linked to issues like cancer and neurological disorders. Lastly, CRISPR has had a major positive impact on the economical side of research by reducing both the time taken and cost of experiments considerably. For instance, CRISPR has enabled researchers to do what previously took a year in just a month! Article 2: Source: Larson, C. Schaffer A. (2016, October 04). New Tools for Editing the Genome Could Radically Change the Study of Human Diseases. Retrieved July 05, 2017, from https://www.technologyreview.com/s/526511/genome-editing/ Genetic editing using the CRISPR-Cas method is revolutionizing the world and has transformed the scenario of many labs throughout the world. It now provides a cheap and highly precise method of gene editing. CRISPR is a tool born from the collaboration between scientists from varied backgrounds pursuing a common goal. Recent research in China has proven the possibility of genetically edited macaques and this is a stepping stone towards â€Å"designer babies†. The introduction of ethical dilemmas due to the advent of this technology is an inevitable repercussion of any powerful tool. However, the success of the aforementioned experiment seeks to showcase the importance of primate models in research. Primate models have also been useful in understanding genetic diseases and mutations and CRISPR now allows researchers to identify these mutations and find gene therapies to it. Article 3: Source: Kiefer, J., Yin, H. H., Que, Q. Q., Mousses, S. (2009). High-throughput siRNA screening as a method of perturbation of biological systems and identification of targeted pathways coupled with compound screening. Retrieved July 05, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/19597791 There are two ways to screen cells containing the CRISPR Cas9 nucleases that knockout specific genes: pooled format and arrayed format. In arrayed screening, the cells and other molecules are arranged in multi well plates (96 wells, 384 wells, or 1536 wells) and the cells that are placed in each of the wells are transfected or virally transduced individually (on a well to well basis). The wells are imaged and then the readout is based upon measurements of those images based on different parameters. In the pooled format, the reagents are synthesized in a pool and are then virally transduced into the cell. Viral transduction ensures that generally only one change to the cell occurs and the integration of the virus can be read through polymerase chain reactions and next-generation screening. The readout of the experiment is based on the abundance of the integrated transgene between samples (in positive selection groups, control groups, and negative selection groups). Article 4: Source: Phillips, T. (2016, October 14). What Is siRNA and How Is It Used to Attack Protein Cells in the Body? Retrieved July 05, 2017, from https://www.thebalance.com/what-is-sirna-and-how-is-it-used-375598 RNA interference (RNAi) is the usage of small interfering RNA (siRNA) that bind to the messenger RNA (mRNA) for specific proteins and cause their degradation hence inhibiting protein synthesis. The siRNA uses a combination of endonuclease and exonuclease enzymes to bring about the degradation of the mRNA. The problem with siRNA is that it can be rejected by the cell and may trigger immune responses. Also, RNAi is known to give false hits and can have an impact on multiple metabolic pathways/mRNAs and cause an unspecific, unwanted, and unknown knockout. However, this method is still very useful in stabilizing serums, enhancing the activity of cells and is also being used in designing therapies for genetic diseases. Article 5: Source: Tan, J., Martin, S. E. (2016, December 28). Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening. Retrieved July 05, 2017, from http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0168968 The research conducted by Tan, J. and Martin, S. E. proves that the viral transfection based CRISPR Cas9 method can be used in the arrayed format by comparing the results of various different techniques and finding conclusive evidence that the results obtained from the arrayed format screening of the cells is similar to that obtained from using the pooled format and RNAi method. They tested their results based on the assay for aberrant DNA replication. Their findings show that the majority of the transfected cells showed a change in phenotype within 72 hours and also that high throughput gene editing and screening of the cells produced data (known DNA replication regulators ) that was comparable to that obtained from siRNA gene knockdown. Lastly, their findings also show that CRISPR screening gave less false hits, i.e. it was more accurate than siRNA screens performed in parallel.

Monday, October 7, 2019

Conversations with History Essay Example | Topics and Well Written Essays - 500 words - 1

Conversations with History - Essay Example Michael Scheuer. Interview with Michael Scheuer Looking at the interview with Mr. Scheuer, it is relevant to say that the answers as his response to all the questions asks came from a point of view of a military whose loyalty lies on the organization and to his country and not to the welfare of the whole world. . According to his belief, if there are things to be learned from the methods being used during the war, this is to kill the enemy as a whole. It has been an experience in their organization that killing them one by one would just only provoke the rest of the enemy. In a war, he considers civilian victims and dead militaries are but just a body counts and a price of the war. For him, during the time of war, enemies must be destroyed by all means as well as the allies and this has been the way of the US to be able to remain in power for 30 years. With regard to the civilians who would be affected and could be killed in the war, Scheuer took it as a part of the war, killing civi lians to be able to win the war or either not to go to war at all.

Sunday, October 6, 2019

FACE reports Research Paper Example | Topics and Well Written Essays - 250 words

FACE reports - Research Paper Example Since the tractor was running, the beaters, three in number, and obtaining energy from the tractor engine, were also rotating (MN FACE). During the process, the farmer got entwined in the machinery, getting pulled into the rotating beaters (MN FACE). As a result, the tractor stopped (MN FACE). He was found forty five minutes later by his son, who immediately called the 911 service, and the farmer was thence taken to a nearby hospital (MN FACE). However, he was pronounced dead on arrival by the doctor (MN FACE). Counter measures: In the wake of the incidence, the FACE team working in Minnesota drafted certain guidelines that were to be followed by farmers and workers while operating heavy machinery (MN FACE). These counter measures included three points (MN FACE): the tractor should be completely switched off and the key removed before getting off the tractor and working on the machinery (MN FACE); the power-take-off mechanism of the machine should be disengaged from the tractor before getting off the tractor and working on the machine (MN FACE); and the outfit of the workers should not be loose or otherwise risky, so that the danger of the workers getting entangled in the machine is reduced (MN